THE NOAEL PROJECT

The No Observed Adverse Effect Level (NOAEL) is a toxicological parameter representing the highest exposure level at which there are no statistically or biologically significant increases in the frequency or severity of adverse effects between the exposed population and its appropriate control.
The Scientific Committee on Consumer Safety (SCCS) now considers NOAEL as the standard requirement in the safety assessment of substances used in cosmetic products. A NOAEL value is indeed essential in order to calculate the Margin of Safety (MOS), that is the ratio bewteen NOAEL and the Systemic Exposure Dose (SED). A MOS under a score of 100 means the substance not safe for being used in cosmetic products.
To address the strong necessity of a database storing solid NOAEL values, we created this website where users that have joined the project can check and download NOAELs found in international peer reviewed journals or databases.
In our toxicological datasheeet we provide all the available information needed for MOS calculation and, if possible, for SED calculation.

NOAEL-SEARCH

From the main menu you can access the search form for the NOAEL of the substances stored in the database. There are two search boxes, one for the INCI name (with autocomplete function) and another one that you can fill with the CAS number or synonyms.

Toxicological informations are only shown for registered users. Anonymous users can only see INCI name and CAS number.

CONTACTS AND SUBSCRIPTION PRICES

For technical info about the NOAEL project visit the FAQ section, if you have more questions, contact Dr. Roberto Narducci:

infoATnoaelproject.it or robymagnoATgmail.com

For info about the cost of subscription click this link, if you have more questions contact Federica Cambiganu:

	federica.cambiganuATpin.unifi.it
	+390574602511
	PIN s.c.r.l. - Piazza Giovanni Ciardi 25, 59100 - Prato

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Substances in database

Download the list (excel format)

Example sheet

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Database access

Last subscription

Herbelia

Nation:

Italy

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Schede aggiornate

We inform you that all the toxicological datasheets in the database have been updated. The broken links have been fixed and the material (where needed) uploaded. Please download the toxicological sheets in case of modifications.

29/10/2020 - 17:03

Category: Website changes

Change of email address

Due to some problems at our servers, you should send email to the following address (not to info@noaelproject.it):

robymagnoATgmail.com

17/07/2020 - 16:02

Category: Attività del sito

Subscription discount

Since all the former subscriptions allowed us to store sufficient money to pay website costs for the next year to come, we decided to temporarily halve the cost for joining the project.
As a consequence, all the active subscriptions will be extended to 10 months for free.

08/11/2015 - 10:50